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Chasing the open-state structure of pentameric ligand-gated ion channels

Remarkable advances have been made toward the structural characterization of ion channels in the last two decades. However, the unambiguous assignment of well-defined functional states to the obtained structural models has proved challenging. In the case of the superfamily of nicotinic-receptor chan...

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Dettagli Bibliografici
Pubblicato in:J Gen Physiol
Autori principali: Gonzalez-Gutierrez, Giovanni, Wang, Yuhang, Cymes, Gisela D., Tajkhorshid, Emad, Grosman, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715906/
https://ncbi.nlm.nih.gov/pubmed/29089419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711803
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