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The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold

The superfamily of pentameric ligand-gated ion channels (pLGICs) is unique among ionotropic receptors in that the same overall structure has evolved to generate multiple members with different combinations of agonist specificities and permeant-ion charge selectivities. However, aside from these diff...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Gonzalez-Gutierrez, Giovanni, Grosman, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485021/
https://ncbi.nlm.nih.gov/pubmed/26078054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411333
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