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Inhibiting 12/15-lipoxygenase to treat acute stroke in permanent and tPA induced thrombolysis models
12/15-Lipoxygenase (12/15-LOX) contributes to the brain damage after middle cerebral artery occlusion (MCAO) in the acute phase of stroke. The aim of this study was to investigate the effects of a 12/15-LOX inhibitor, LOXBlock-1(LB1), in mice using a FeCl(3)-induced permanent distal MCAO model and F...
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| Veröffentlicht in: | Brain Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714685/ https://ncbi.nlm.nih.gov/pubmed/29079502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2017.10.024 |
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