Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke

Targeting newly identified damage pathways in the ischemic brain can help to circumvent the currently severe limitations of acute stroke therapy. Here we show that the activity of 12/15-lipoxygenase was increased in the ischemic mouse brain, and 12/15-lipoxygenase co-localized with a marker for oxid...

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Autori principali: Yigitkanli, Kazim, Pekcec, Anton, Karatas, Hulya, Pallast, Stefanie, Mandeville, Emiri, Joshi, Netra, Smirnova, Natalya, Gazaryan, Irina, Ratan, Rajiv R., Witztum, Joseph L., Montaner, Joan, Holman, Theodore R., Lo, Eng H., van Leyen, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563836/
https://ncbi.nlm.nih.gov/pubmed/23192915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23734
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