Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke

Targeting newly identified damage pathways in the ischemic brain can help to circumvent the currently severe limitations of acute stroke therapy. Here we show that the activity of 12/15-lipoxygenase was increased in the ischemic mouse brain, and 12/15-lipoxygenase co-localized with a marker for oxid...

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Detalhes bibliográficos
Main Authors: Yigitkanli, Kazim, Pekcec, Anton, Karatas, Hulya, Pallast, Stefanie, Mandeville, Emiri, Joshi, Netra, Smirnova, Natalya, Gazaryan, Irina, Ratan, Rajiv R., Witztum, Joseph L., Montaner, Joan, Holman, Theodore R., Lo, Eng H., van Leyen, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563836/
https://ncbi.nlm.nih.gov/pubmed/23192915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23734
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