12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress

12/15-Lipoxygenase (12/15-LOX) is an important mediator of brain injury following experimental stroke in rodents. It contributes to neuronal death, but the underlying mechanism remains unclear. We demonstrate here that in neuronal HT22 cells subjected to glutamate-induced oxidative stress, 12/15-LOX...

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Detaylı Bibliyografya
Asıl Yazarlar: Pallast, Stefanie, Arai, Ken, Wang, Xiaoying, Lo, Eng H., van Leyen, Klaus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773137/
https://ncbi.nlm.nih.gov/pubmed/19737346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06379.x
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