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12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress
12/15-Lipoxygenase (12/15-LOX) is an important mediator of brain injury following experimental stroke in rodents. It contributes to neuronal death, but the underlying mechanism remains unclear. We demonstrate here that in neuronal HT22 cells subjected to glutamate-induced oxidative stress, 12/15-LOX...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773137/ https://ncbi.nlm.nih.gov/pubmed/19737346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06379.x |
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