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12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress

12/15-Lipoxygenase (12/15-LOX) is an important mediator of brain injury following experimental stroke in rodents. It contributes to neuronal death, but the underlying mechanism remains unclear. We demonstrate here that in neuronal HT22 cells subjected to glutamate-induced oxidative stress, 12/15-LOX...

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Sonraí Bibleagrafaíochta
Main Authors: Pallast, Stefanie, Arai, Ken, Wang, Xiaoying, Lo, Eng H., van Leyen, Klaus
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773137/
https://ncbi.nlm.nih.gov/pubmed/19737346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06379.x
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