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Increased 12/15-Lipoxygenase leads to Widespread Brain Injury Following Global Cerebral Ischemia

Global ischemia following cardiac arrest is characterized by high mortality and significant neurological deficits in long-term survivors. Its mechanisms of neuronal cell death have only partially been elucidated. 12/15-lipoxygenase (12/15-LOX) is a major contributor to delayed neuronal cell death an...

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Bibliographic Details
Published in:Transl Stroke Res
Main Authors: Yigitkanli, Kazim, Zheng, Yi, Pekcec, Anton, Lo, Eng H., van Leyen, Klaus
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350054/
https://ncbi.nlm.nih.gov/pubmed/27838820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-016-0509-z
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