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A rat model of studying tPA thrombolysis in ischemic stroke with diabetes

BACKGROUND AND PURPOSE: Post-stroke hyperglycemia and diabetes mellitus are associated with lower thrombolytic efficacy and an increased risk of post-ischemic cerebral hemorrhage. We aimed to develop a rodent model of thrombolysis in diabetic stroke that mimics the clinical situation. METHOD: Male 6...

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Detalhes bibliográficos
Main Authors: Fan, Xiang, Qiu, Jianhua, Yu, Zhanyang, Dai, Haibin, Singhal, Aneesh B., Lo, Eng H., Wang, Xiaoying
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508716/
https://ncbi.nlm.nih.gov/pubmed/22052516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.635250
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