Low dose tPA plus annexin A2 combination attenuates tPA delayed treatment-associated hemorrhage and improves recovery in rat embolic focal stroke

We previously have shown that tissue type plasminogen activator (tPA) in combination with its receptor annexin A2 (rA2) protein significantly improved tPA thrombolytic efficacy. In this study we aimed to examine the therapeutic effects of the combination when treated at delayed 4-hourwindow after st...

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Udgivet i:Neurosci Lett
Main Authors: Jiang, Yinghua, Fan, Xiang, Yu, Zhanyang, Cheng, Chongjie, Wang, Xiao-Shu, Lo, Eng H., Sun, Xiaochuan, Wang, Xiaoying
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739853/
https://ncbi.nlm.nih.gov/pubmed/26149229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.06.050
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