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Iron accumulation and dysregulation in the putamen in fragile X associated tremor/ataxia syndrome

BACKGROUND: Fragile X-associated tremor/ataxia Syndrome (FXTAS) is an adult-onset disorder associated with premutation alleles of the FMR1 gene. The disorder is characterized by progressive action tremor, gait ataxia, and cognitive decline. FXTAS pathology includes dystrophic white matter and intran...

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Dettagli Bibliografici
Pubblicato in:Mov Disord
Autori principali: Ariza, Jeanelle, Rogers, Hailee, Hartvigsen, Anna, Snell, Melissa, Dill, Michael, Judd, Derek, Hagerman, Paul, Martínez-Cerdeño
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714315/
https://ncbi.nlm.nih.gov/pubmed/28233916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26902
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