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Iron accumulation and dysregulation in the putamen in fragile X associated tremor/ataxia syndrome

BACKGROUND: Fragile X-associated tremor/ataxia Syndrome (FXTAS) is an adult-onset disorder associated with premutation alleles of the FMR1 gene. The disorder is characterized by progressive action tremor, gait ataxia, and cognitive decline. FXTAS pathology includes dystrophic white matter and intran...

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Foilsithe in:Mov Disord
Main Authors: Ariza, Jeanelle, Rogers, Hailee, Hartvigsen, Anna, Snell, Melissa, Dill, Michael, Judd, Derek, Hagerman, Paul, Martínez-Cerdeño
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714315/
https://ncbi.nlm.nih.gov/pubmed/28233916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26902
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