Quantitation of ortho-Cresyl Phosphate Adducts to Butyrylcholinesterase in Human Serum by Immunomagnetic-UHPLC-MS/MS

Tri-ortho-cresyl phosphate (ToCP) is an anti-wear, flame retardant additive used in industrial lubricants, hydraulic fluids, and gasoline. The neurotoxic effects of ToCP arise from the liver-activated metabolite 2-(o-cresyl)-4H-1,3,2-benzodioxaphosphoran-2-one (cresyl saligenin phosphate or CBDP), w...

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Detalhes bibliográficos
Publicado no:J Mass Spectrom
Main Authors: Johnson, Darryl, Carter, Melissa D., Crow, Brian S., Isenberg, Samantha L., Graham, Leigh Ann, Erol, H. Akin, Watson, Caroline M., Pantazides, Brooke G., van der Schans, Marcel J., Langenberg, Jan P., Noort, Daan, Blake, Thomas A., Thomas, Jerry D., Johnson, Rudolph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713888/
https://ncbi.nlm.nih.gov/pubmed/26149113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.3576
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