High-Confidence Qualitative Identification of Organophosphorus Nerve Agent Adducts to Human Butyrylcholinesterase

In this study, a data-dependent, high-resolution tandem mass spectrometry (ddHRMS/MS) method capable of detecting all organophosphorus nerve agent (OPNA) adducts to human butyrylcholinesterase (BChE) was developed. After an exposure event, immunoprecipitation from blood with a BChE-specific antibody...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Mathews, Thomas P., Carter, Melissa D., Johnson, Darryl, Isenberg, Samantha L., Graham, Leigh Ann, Thomas, Jerry D., Johnson, Rudolph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713887/
https://ncbi.nlm.nih.gov/pubmed/28208252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b04441
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