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Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

Autophagy is central to the maintenance of organismal homeostasis in both physiological and pathological situations. Accordingly, alterations in autophagy have been linked to clinically relevant conditions as diverse as cancer, neurodegeneration and cardiac disorders. Throughout the past decade, aut...

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Publicat a:Nat Rev Drug Discov
Autors principals: Galluzzi, Lorenzo, Bravo-San Pedro, José Manuel, Levine, Beth, Green, Douglas R., Kroemer, Guido
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713640/
https://ncbi.nlm.nih.gov/pubmed/28529316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2017.22
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