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Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

Autophagy is central to the maintenance of organismal homeostasis in both physiological and pathological situations. Accordingly, alterations in autophagy have been linked to clinically relevant conditions as diverse as cancer, neurodegeneration and cardiac disorders. Throughout the past decade, aut...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Galluzzi, Lorenzo, Bravo-San Pedro, José Manuel, Levine, Beth, Green, Douglas R., Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713640/
https://ncbi.nlm.nih.gov/pubmed/28529316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2017.22
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