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Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles

A large body of evidence indicates that mitochondrial dysfunction has a major role in the pathogenesis of multiple cardiovascular disorders. Over the past 2 decades, extraordinary efforts have been focused on the development of agents that specifically target mitochondria for the treatment of cardio...

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Détails bibliographiques
Publié dans:Nat Rev Cardiol
Auteurs principaux: Bonora, Massimo, Wieckowski, Mariusz R., Sinclair, David A., Kroemer, Guido, Pinton, Paolo, Galluzzi, Lorenzo
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349394/
https://ncbi.nlm.nih.gov/pubmed/30177752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41569-018-0074-0
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