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Mitochondria and the autophagy-inflammation-cell death axis in organismal aging

Alterations of mitochondrial functions are linked to multiple degenerative or acute diseases. As mitochondria age in our cells, they become progressively inefficient and potentially toxic, and acute damage can trigger the permeabilization of mitochondrial membranes to initiate apoptosis or necrosis....

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Bibliografische gegevens
Hoofdauteurs: Green, Douglas R., Galluzzi, Lorenzo, Kroemer, Guido
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405151/
https://ncbi.nlm.nih.gov/pubmed/21868666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1201940
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