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Nitric Oxide Mediates Crosstalk between Interleukin 1β and WNT Signaling in Primary Human Chondrocytes by Reducing DKK1 and FRZB Expression

Interleukin 1 beta (IL1β) and Wingless-Type MMTV Integration Site Family (WNT) signaling are major players in Osteoarthritis (OA) pathogenesis. Despite having a large functional overlap in OA onset and development, the mechanism of IL1β and WNT crosstalk has remained largely unknown. In this study,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Mol Sci
मुख्य लेखकों: Zhong, Leilei, Schivo, Stefano, Huang, Xiaobin, Leijten, Jeroen, Karperien, Marcel, Post, Janine N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713457/
https://ncbi.nlm.nih.gov/pubmed/29165387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18112491
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