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Altered phosphorylation, electrophysiology, and behavior on attenuation of PDE4B action in hippocampus

BACKGROUND: PDE4 cyclic nucleotide phosphodiesterases regulate 3′, 5′ cAMP abundance in the CNS and thereby regulate PKA activity and phosphorylation of CREB, which has been implicated in learning and memory, depression and other functions. The PDE4 isoform PDE4B1 also interacts with the DISC1 prote...

詳細記述

保存先:
書誌詳細
出版年:BMC Neurosci
主要な著者: Campbell, Susan L., van Groen, Thomas, Kadish, Inga, Smoot, Lisa High Mitchell, Bolger, Graeme B.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712142/
https://ncbi.nlm.nih.gov/pubmed/29197324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0396-6
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