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Hunger in the Absence of Caloric Restriction Improves Cognition and Attenuates Alzheimer's Disease Pathology in a Mouse Model

It has been shown that caloric restriction (CR) delays aging and possibly delays the development of Alzheimer's disease (AD). We conjecture that the mechanism may involve interoceptive cues, rather than reduced energy intake per se. We determined that hunger alone, induced by a ghrelin agonist,...

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Detalhes bibliográficos
Main Authors: Dhurandhar, Emily J., Allison, David B., van Groen, Thomas, Kadish, Inga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614512/
https://ncbi.nlm.nih.gov/pubmed/23565247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060437
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