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Memantine Attenuates Alzheimer’s Disease-Like Pathology and Cognitive Impairment

Deficiency of protein phosphatase-2A is a key event in Alzheimer’s disease. An endogenous inhibitor of protein phosphatase-2A, inhibitor-1, I(1) (PP2A), which inhibits the phosphatase activity by interacting with its catalytic subunit protein phosphatase-2Ac, is known to be upregulated in Alzheimer’...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wang, Xiaochuan, Blanchard, Julie, Grundke-Iqbal, Inge, Iqbal, Khalid
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689401/
https://ncbi.nlm.nih.gov/pubmed/26697860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145441
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