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Alzheimer disease and amyotrophic lateral sclerosis: An etiopathogenic connection

The etiopathogenesis of neither the sporadic form of Alzheimer disease (AD) nor of amyotrophic lateral sclerosis (ALS) are well understood. The activity of protein phosphatase-2A (PP2A), which regulates the phosphorylation of tau and neurofilaments, is negatively regulated by the myeloid leukemia-as...

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Bibliografiske detaljer
Main Authors: Wang, Xiaochuan, Blanchard, Julie, Grundke-Iqbal, Inge, Wegiel, Jerzy, Deng, Han-Xiang, Siddique, Teepu, Iqbal, Khalid
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947003/
https://ncbi.nlm.nih.gov/pubmed/24136402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1175-9
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