Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β(1) and Shh Signalling

Diabetes is a risk factor for acute kidney injury (AKI) and chronic kidney disease (CKD). Diabetic patients are easy to progress to CKD after AKI. Currently, activation of fibrotic signalling including transforming growth factor-β(1) (TGF-β(1)) is recognized as a key mechanism in CKD. Here, we inves...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kim, Dong-Jin, Kang, Jun Mo, Park, Seon Hwa, Kwon, Hyuk-Kwon, Song, Seok-Jong, Moon, Haena, Kim, Su-Mi, Seo, Jung-Woo, Lee, Yu Ho, Kim, Yang Gyun, Moon, Ju-Young, Lee, So-Young, Son, Youngsook, Lee, Sang-Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711892/
https://ncbi.nlm.nih.gov/pubmed/29196746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16977-z
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