Kainic Acid-induced Neuronal Death is Attenuated by Aminoguanidine but Aggravated by L-NAME in Mouse Hippocampus

Nitric oxide (NO) has both neuroprotective and neurotoxic effects depending on its concentration and the experimental model. We tested the effects of NG-nitro-L-arginine methyl ester (L-NAME), a nonselective nitric oxide synthase (NOS) inhibitor, and aminoguanidine, a selective inducible NOS (iNOS)...

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Detalhes bibliográficos
Main Authors: Byun, Jong-Seon, Lee, Sang-Hyun, Jeon, Seong-Ho, Kwon, Yong-Soo, Lee, Hee Jae, Kim, Sung-Soo, Kim, Young-Myeong, Kim, Myong-Jo, Chun, Wanjoo
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766714/
https://ncbi.nlm.nih.gov/pubmed/19885009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.4.265
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