Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β(1) and Shh Signalling

Diabetes is a risk factor for acute kidney injury (AKI) and chronic kidney disease (CKD). Diabetic patients are easy to progress to CKD after AKI. Currently, activation of fibrotic signalling including transforming growth factor-β(1) (TGF-β(1)) is recognized as a key mechanism in CKD. Here, we inves...

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Publicado no:Sci Rep
Main Authors: Kim, Dong-Jin, Kang, Jun Mo, Park, Seon Hwa, Kwon, Hyuk-Kwon, Song, Seok-Jong, Moon, Haena, Kim, Su-Mi, Seo, Jung-Woo, Lee, Yu Ho, Kim, Yang Gyun, Moon, Ju-Young, Lee, So-Young, Son, Youngsook, Lee, Sang-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711892/
https://ncbi.nlm.nih.gov/pubmed/29196746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16977-z
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