PGC1α Activators Mitigate Diabetic Tubulopathy by Improving Mitochondrial Dynamics and Quality Control

Purpose. In this study, we investigated the effect of PGC1α activators on mitochondrial fusion, fission, and autophagic quality control in renal tubular cells in a diabetic environment in vivo and in vitro. We also examined whether the upregulation of PGC1α attenuates diabetic tubulopathy by normali...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Lee, So-Young, Kang, Jun Mo, Kim, Dong-Jin, Park, Seon Hwa, Jeong, Hye Yun, Lee, Yu Ho, Kim, Yang Gyun, Yang, Dong Ho, Lee, Sang Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376939/
https://ncbi.nlm.nih.gov/pubmed/28409163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6483572
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