Necdin shapes serotonergic development and SERT activity modulating breathing in a mouse model for Prader-Willi syndrome

Prader-Willi syndrome (PWS) is a genetic neurodevelopmental disorder that presents with hypotonia and respiratory distress in neonates. The Necdin-deficient mouse is the only model that reproduces the respiratory phenotype of PWS (central apnea and blunted response to respiratory challenges). Here,...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Matarazzo, Valéry, Caccialupi, Laura, Schaller, Fabienne, Shvarev, Yuri, Kourdougli, Nazim, Bertoni, Alessandra, Menuet, Clément, Voituron, Nicolas, Deneris, Evan, Gaspar, Patricia, Bezin, Laurent, Durbec, Pascale, Hilaire, Gérard, Muscatelli, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Human Biology and Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711373/
https://ncbi.nlm.nih.gov/pubmed/29087295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32640
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