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Perturbation of the T cell receptor repertoire occurs with increasing age in dogs

Immunosenescence is the gradual deterioration in immune system function associated with ageing. This decline is partly due to involution of the thymus, which leads to a reduction in the output of naive T cells into the circulating lymphocyte pool. Expansion of existing naive and memory T cell popula...

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Detalhes bibliográficos
Publicado no:Dev Comp Immunol
Main Authors: Holder, Angela, Mirczuk, Samantha M., Fowkes, Robert C., Palmer, Donald B., Aspinall, Richard, Catchpole, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711257/
https://ncbi.nlm.nih.gov/pubmed/29103899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dci.2017.10.020
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