An Age-Associated Decline in Thymic Output Differs in Dog Breeds According to Their Longevity

The age associated decline in immune function is preceded in mammals by a reduction in thymic output. Furthermore, there is increasing evidence of a link between immune competence and lifespan. One approach to determining thymic output is to quantify signal joint T cell receptor excision circles (sj...

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Bibliographic Details
Published in:PLoS One
Main Authors: Holder, Angela, Mella, Stephanie, Palmer, Donald B., Aspinall, Richard, Catchpole, Brian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100965/
https://ncbi.nlm.nih.gov/pubmed/27824893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165968
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