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Disruption of K(V)2.1 somato-dendritic clusters prevents the apoptogenic increase of potassium currents

As the predominant mediator of the delayed rectifier current, K(V)2.1 is an important regulator of neuronal excitability. K(V)2.1, however, also plays a well-established role in apoptotic cell death. Apoptogenic stimuli induce syntaxin-dependent trafficking of K(V)2.1, resulting in an augmented dela...

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Détails bibliographiques
Publié dans:Neuroscience
Auteurs principaux: Justice, Jason A., Schulien, Anthony J., He, Kai, Hartnett, Karen A., Aizenman, Elias, Shah, Niyathi H.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709998/
https://ncbi.nlm.nih.gov/pubmed/28461216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.04.034
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