Cyclin E1 Regulates Kv2.1 Channel Phosphorylation and Localization in Neuronal Ischemia

Kv2.1 is a major delayed rectifying K(+) channel normally localized to highly phosphorylated somatodendritic clusters in neurons. Excitatory stimuli induce calcineurin-dependent dephosphorylation and dispersal of Kv2.1 clusters, with a concomitant hyperpolarizing shift in the channel's activati...

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Detalhes bibliográficos
Main Authors: Shah, Niyathi H., Schulien, Anthony J., Clemens, Katerina, Aizenman, Talia D., Hageman, Thomas M., Wills, Zachary P., Aizenman, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960471/
https://ncbi.nlm.nih.gov/pubmed/24647953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5184-13.2014
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