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Regulation of Pro-Apoptotic Phosphorylation of Kv2.1 K(+) Channels

Caspase activity during apoptosis is inhibited by physiological concentrations of intracellular K(+). To enable apoptosis in injured cortical and hippocampal neurons, cellular loss of this cation is facilitated by the insertion of Kv2.1 K(+) channels into the plasma membrane via a Zn(2+)/CaMKII/SNAR...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: He, Kai, McCord, Meghan C., Hartnett, Karen A., Aizenman, Elias
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482604/
https://ncbi.nlm.nih.gov/pubmed/26115091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129498
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