Syntaxin-binding domain of Kv2.1 is essential for the expression of apoptotic K(+) currents

Intracellular signalling cascades triggered by oxidative injury can lead to upregulation of Kv2.1 K(+) channels at the plasma membrane of dying neurons. Membrane incorporation of new channels is necessary for enhanced K(+) efflux and a consequent reduction of intracellular K(+) that facilitates apop...

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Publicado en:J Physiol
Autores principales: McCord, Meghan C, Kullmann, Paul H, He, Kai, Hartnett, Karen A, Horn, John P, Lotan, Ilana, Aizenman, Elias
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
Materias:
Neuroscience: Cellular/Molecular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229345/
https://ncbi.nlm.nih.gov/pubmed/24928958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.276964
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