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Isoform‐specific localization of DNMT3A regulates DNA methylation fidelity at bivalent CpG islands

DNA methylation is a prevalent epigenetic modification involved in transcriptional regulation and essential for mammalian development. While the genome‐wide distribution of this mark has been studied to great detail, the mechanisms responsible for its correct deposition, as well as the cause for its...

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Foilsithe in:EMBO J
Main Authors: Manzo, Massimiliano, Wirz, Joël, Ambrosi, Christina, Villaseñor, Rodrigo, Roschitzki, Bernd, Baubec, Tuncay
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709737/
https://ncbi.nlm.nih.gov/pubmed/29074627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797038
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