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Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes
CpG, 5′-C-phosphate-G-3′, islands (CGIs) have long been known for their association with enhancers, silencers, and promoters, and for their epigenetic signatures. They are maintained in embryonic stem cells (ESCs) in a poised but inactive state via the formation of bivalent chromatin containing both...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347632/ https://ncbi.nlm.nih.gov/pubmed/28223506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613300114 |
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