Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes

CpG, 5′-C-phosphate-G-3′, islands (CGIs) have long been known for their association with enhancers, silencers, and promoters, and for their epigenetic signatures. They are maintained in embryonic stem cells (ESCs) in a poised but inactive state via the formation of bivalent chromatin containing both...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lee, Sun-Min, Lee, Jungwoo, Noh, Kyung-Min, Choi, Won-Young, Jeon, Sejin, Oh, Goo Taeg, Kim-Ha, Jeongsil, Jin, Yoonhee, Cho, Seung-Woo, Kim, Young-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347632/
https://ncbi.nlm.nih.gov/pubmed/28223506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613300114
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