Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa

BACKGROUND: CpG methylation of tumor suppressor genes occurs in the early stage of carcinogenesis. Detecting risk factors for aberrant CpG methylation is clinically important for predicting cancer development. DNA methyltransferase (DNMT) 3a is considered to play critical roles in the DNA methylatio...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Takano, Hikaru, Shibata, Tomoyuki, Nakamura, Masakatsu, Sakurai, Naoko, Hayashi, Tasuku, Ota, Masafumi, Nomura-Horita, Tomoe, Hayashi, Ranji, Shimasaki, Takeo, Otsuka, Toshimi, Tahara, Tomomitsu, Arisawa, Tomiyasu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562764/
https://ncbi.nlm.nih.gov/pubmed/33066747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-020-01142-7
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