Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa

BACKGROUND: CpG methylation of tumor suppressor genes occurs in the early stage of carcinogenesis. Detecting risk factors for aberrant CpG methylation is clinically important for predicting cancer development. DNA methyltransferase (DNMT) 3a is considered to play critical roles in the DNA methylatio...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Med Genet
Auteurs principaux: Takano, Hikaru, Shibata, Tomoyuki, Nakamura, Masakatsu, Sakurai, Naoko, Hayashi, Tasuku, Ota, Masafumi, Nomura-Horita, Tomoe, Hayashi, Ranji, Shimasaki, Takeo, Otsuka, Toshimi, Tahara, Tomomitsu, Arisawa, Tomiyasu
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562764/
https://ncbi.nlm.nih.gov/pubmed/33066747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-020-01142-7
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