Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa

BACKGROUND: CpG methylation of tumor suppressor genes occurs in the early stage of carcinogenesis. Detecting risk factors for aberrant CpG methylation is clinically important for predicting cancer development. DNA methyltransferase (DNMT) 3a is considered to play critical roles in the DNA methylatio...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Med Genet
Main Authors: Takano, Hikaru, Shibata, Tomoyuki, Nakamura, Masakatsu, Sakurai, Naoko, Hayashi, Tasuku, Ota, Masafumi, Nomura-Horita, Tomoe, Hayashi, Ranji, Shimasaki, Takeo, Otsuka, Toshimi, Tahara, Tomomitsu, Arisawa, Tomiyasu
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562764/
https://ncbi.nlm.nih.gov/pubmed/33066747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-020-01142-7
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