Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction

Recently, it has been reported that human hepatocyte-like cells can be generated from fibroblasts by direct reprogramming technology. However, the conversion efficiency of human induced hepatocyte-like cells (hiHeps) is not high enough. In addition, comparative analysis with the existing models of h...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Nakamori, Daiki, Akamine, Hiroki, Takayama, Kazuo, Sakurai, Fuminori, Mizuguchi, Hiroyuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709502/
https://ncbi.nlm.nih.gov/pubmed/29192290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16856-7
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