Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling

The function of hepatocytes largely depends on their position in the liver lobule. Although the method of differentiating hepatocytes from human pluripotent stem cells has been largely improved over the past decade, there remains no technique for generating hepatocyte-like cells (HLCs) with zone-spe...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther
Asıl Yazarlar: Mitani, Seiji, Takayama, Kazuo, Nagamoto, Yasuhito, Imagawa, Kazuo, Sakurai, Fuminori, Tachibana, Masashi, Sumazaki, Ryo, Mizuguchi, Hiroyuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475257/
https://ncbi.nlm.nih.gov/pubmed/28462819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.04.006
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