Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection

In order to understand the life cycle of hepatitis B virus (HBV) and to develop efficient anti-HBV drugs, a useful in vitro cell culture system which allows HBV infection and recapitulates virus-host interactions is essential; however, pre-existing in vitro HBV infection models are often problematic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sakurai, Fuminori, Mitani, Seiji, Yamamoto, Tatsuro, Takayama, Kazuo, Tachibana, Masashi, Watashi, Koichi, Wakita, Takaji, Iijima, Sayuki, Tanaka, Yasuhito, Mizuguchi, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379564/
https://ncbi.nlm.nih.gov/pubmed/28374759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45698
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