Generation of metabolically functional hepatocyte‐like cells from dedifferentiated fat cells by Foxa2, Hnf4a and Sall1 transduction

Mature adipocyte‐derived dedifferentiated fat (DFAT) cells have been identified to possess similar multipotency to mesenchymal stem cells, but a method for converting DFAT cells into hepatocytes was previously unknown. Here, using comprehensive analysis of gene expression profiles, we have extracted...

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Publicat a:Genes Cells
Autors principals: Hagiwara, Reiko, Oki, Yoshinao, Matsumaru, Takashi, Ibayashi, Shiho, Kano, Koichiro
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894465/
https://ncbi.nlm.nih.gov/pubmed/33064855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12814
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