A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice

Mouse models have contributed to the bulk of knowledge on Systemic Lupus Erythematosus (SLE). Nevertheless, substantial differences exist between human and mouse immune system. We aimed to establish and characterise a SLE model mediated by human immune system. Injection of pristane into immunodefici...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Gunawan, Merry, Her, Zhisheng, Liu, Min, Tan, Sue Yee, Chan, Xue Ying, Tan, Wilson Wei Sheng, Dharmaraaja, Shubasree, Fan, Yong, Ong, Chee Bing, Loh, Eva, Chang, Kenneth Tou En, Tan, Thiam Chye, Chan, Jerry Kok Yen, Chen, Qingfeng
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709358/
https://ncbi.nlm.nih.gov/pubmed/29192160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16999-7
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