A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice

Mouse models have contributed to the bulk of knowledge on Systemic Lupus Erythematosus (SLE). Nevertheless, substantial differences exist between human and mouse immune system. We aimed to establish and characterise a SLE model mediated by human immune system. Injection of pristane into immunodefici...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gunawan, Merry, Her, Zhisheng, Liu, Min, Tan, Sue Yee, Chan, Xue Ying, Tan, Wilson Wei Sheng, Dharmaraaja, Shubasree, Fan, Yong, Ong, Chee Bing, Loh, Eva, Chang, Kenneth Tou En, Tan, Thiam Chye, Chan, Jerry Kok Yen, Chen, Qingfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709358/
https://ncbi.nlm.nih.gov/pubmed/29192160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16999-7
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