Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy

OBJECTIVE: As the current therapeutic strategies for human hepatocellular carcinoma (HCC) have been proven to have limited effectiveness, immunotherapy becomes a compelling way to tackle the disease. We aim to provide humanised mouse (humice) models for the understanding of the interaction between h...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Zhao, Yue, Shuen, Timothy Wai Ho, Toh, Tan Boon, Chan, Xue Ying, Liu, Min, Tan, Sue Yee, Fan, Yong, Yang, Hechuan, Lyer, Shridhar Ganpathi, Bonney, Glenn Kunnath, Loh, Eva, Chang, Kenneth Tou En, Tan, Thiam Chye, Zhai, Weiwei, Chan, Jerry Kok Yen, Chow, Edward Kai-Hua, Chee, Cheng Ean, Lee, Guan Huei, Dan, Yock Young, Chow, Pierce Kah-Hoe, Toh, Han Chong, Lim, Seng Gee, Chen, Qingfeng
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
GI cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145285/
https://ncbi.nlm.nih.gov/pubmed/29602780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-315201
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