A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice

Mouse models have contributed to the bulk of knowledge on Systemic Lupus Erythematosus (SLE). Nevertheless, substantial differences exist between human and mouse immune system. We aimed to establish and characterise a SLE model mediated by human immune system. Injection of pristane into immunodefici...

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Pubblicato in:Sci Rep
Autori principali: Gunawan, Merry, Her, Zhisheng, Liu, Min, Tan, Sue Yee, Chan, Xue Ying, Tan, Wilson Wei Sheng, Dharmaraaja, Shubasree, Fan, Yong, Ong, Chee Bing, Loh, Eva, Chang, Kenneth Tou En, Tan, Thiam Chye, Chan, Jerry Kok Yen, Chen, Qingfeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709358/
https://ncbi.nlm.nih.gov/pubmed/29192160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16999-7
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