Age-dependent insulin resistance in male mice with null deletion of the carcinoembryonic antigen-related cell adhesion molecule 2 gene

AIMS/HYPOTHESIS: Cc2(−/−) mice lacking the gene of the carcinoembryonic-antigen-related cell adhesion molecule 2 [Cc2 (also known as Ceacam2)] exhibit hyperphagia that leads to obesity and insulin resistance. This starts at 2 months of age in female mice. Male mutants maintain normal body weight and...

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Detaylı Bibliyografya
Yayımlandı:Diabetologia
Asıl Yazarlar: Ghanem, Simona S., Muturi, Harrison T., DeAngelis, Anthony M., Hu, Jiang, Kulkarni, Rohit N., Heinrich, Garrett, Najjar, Sonia M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709176/
https://ncbi.nlm.nih.gov/pubmed/28567513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4307-2
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