Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1: A Link Between Insulin and Lipid Metabolism

OBJECTIVE—Liver-specific inactivation of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) by a dominant-negative transgene (l-SACC1 mice) impaired insulin clearance, caused insulin resistance, and increased hepatic lipogenesis. To discern whether this phenotype reflects a physiolo...

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Autori principali: DeAngelis, Anthony M., Heinrich, Garrett, Dai, Tong, Bowman, Thomas A., Patel, Payal R., Lee, Sang Jun, Hong, Eun-Gyoung, Jung, Dae Young, Assmann, Anke, Kulkarni, Rohit N., Kim, Jason K., Najjar, Sonia M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2008
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518480/
https://ncbi.nlm.nih.gov/pubmed/18544705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0379
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