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Age-dependent insulin resistance in male mice with null deletion of the carcinoembryonic antigen-related cell adhesion molecule 2 gene
AIMS/HYPOTHESIS: Cc2(−/−) mice lacking the gene of the carcinoembryonic-antigen-related cell adhesion molecule 2 [Cc2 (also known as Ceacam2)] exhibit hyperphagia that leads to obesity and insulin resistance. This starts at 2 months of age in female mice. Male mutants maintain normal body weight and...
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| Udgivet i: | Diabetologia |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709176/ https://ncbi.nlm.nih.gov/pubmed/28567513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4307-2 |
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