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Effect of MDR1 C1236T polymorphism on cyclosporine pharmacokinetics: A systematic review and meta-analysis

BACKGROUND: Cyclosporine (CsA) is one of the immunosuppressive drugs, whose pharmacokinetic characteristics vary greatly among individuals. The published data reveal conflicting effects of the polymorphism of MDR1 exon 12 SNP C1236T on the pharmacokinetics of cyclosporine. This study aims to conduct...

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Dades bibliogràfiques
Publicat a:Medicine (Baltimore)
Autors principals: Chen, Zhe, Zhang, Lingli, Yang, Chunsong, Jiang, Zhimei, Shen, Hongxin, Gui, Ge
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Health 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708953/
https://ncbi.nlm.nih.gov/pubmed/29381954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000008700
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