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Effect of MDR1 C1236T polymorphism on cyclosporine pharmacokinetics: A systematic review and meta-analysis

BACKGROUND: Cyclosporine (CsA) is one of the immunosuppressive drugs, whose pharmacokinetic characteristics vary greatly among individuals. The published data reveal conflicting effects of the polymorphism of MDR1 exon 12 SNP C1236T on the pharmacokinetics of cyclosporine. This study aims to conduct...

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Dettagli Bibliografici
Pubblicato in:Medicine (Baltimore)
Autori principali: Chen, Zhe, Zhang, Lingli, Yang, Chunsong, Jiang, Zhimei, Shen, Hongxin, Gui, Ge
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer Health 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708953/
https://ncbi.nlm.nih.gov/pubmed/29381954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000008700
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