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Accounting for patient heterogeneity in phase II clinical trials
Phase II clinical trials typically are single-arm studies conducted to decide whether an experimental treatment is sufficiently promising, relative to standard treatment, to warrant further investigation. Many methods exist for conducting phase II trials under the assumption that patients are homoge...
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| Publicado no: | Stat Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5708894/ https://ncbi.nlm.nih.gov/pubmed/17948869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3109 |
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